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MRGPRX2 抗体 (Middle Region)

MRGPRX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788260
发货至: 中国
  • 抗原 See all MRGPRX2 抗体
    MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 30
    • 2
    • 1
    宿主
    • 27
    • 3
    克隆类型
    • 29
    • 1
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This MRGPRX2 antibody is un-conjugated
    应用范围
    • 20
    • 18
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VCVLLWALSL LLSILEGKFC GFLFSDGDSG WCQTFDFITA AWLIFLFMVL
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against MRGPRX2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MRGPRX2
    Top Product
    Discover our top product MRGPRX2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 330 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
    别名
    MRGPRX2 (MRGPRX2 产品)
    别名
    MRGX2 antibody, G370024M05Rik antibody, MrgB10 antibody, Mrgprb10 antibody, MrgB1 antibody, Mrgprb1 antibody, MAS related GPR family member X2 antibody, MAS-related GPR, member X2 antibody, MRGPRX2 antibody, Mrgprx2 antibody
    背景
    MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
    Alias Symbols: MRGX2
    Protein Interaction Partner: CORT,
    Protein Size: 330
    分子量
    37 kDa
    基因ID
    117194
    NCBI登录号
    NM_054030, NP_473371
    UniProt
    Q96LB1
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