-
- 抗原 See all PCSK1N 抗体
- PCSK1N (Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N))
-
抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PCSK1N antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- STPLRLRRAV PRGEAAGAVQ ELARALAHLL EAERQERARA EAQEAEDQQA
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Pcsk1n. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Pcsk1n
- Top Product
- Discover our top product PCSK1N Primary Antibody
-
anti-Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N) (AA 173-260) antibody
PCSK1N 适用: 人 ELISA, WB, IHC (p), IF 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N) (AA 1-260) antibodyPCSK1N 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N) (Internal Region) antibodyVerified PCSK1N 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N) (AA 54-103) antibodyPCSK1N 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 260 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- PCSK1N (Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N))
- 别名
- Pcsk1n (PCSK1N 产品)
- 别名
- PROSAAS antibody, SAAS antibody, Saas antibody, AI848336 antibody, KEP antibody, PEN antibody, PEN19 antibody, PEN20 antibody, Pan3 antibody, SAASCT antibody, bLEN antibody, lLEN antibody, proSAAS antibody, proprotein convertase subtilisin/kexin type 1 inhibitor antibody, PCSK1N antibody, Pcsk1n antibody
- 背景
-
Pcsk1n may function in the control of the neuroendocrine secretory pathway. It is proposed to be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 87 kDa form but not the autocatalytically derived 65 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. Pcsk1n may control the intracellular timing of PCSK1 rather than its total level of activity. The function of the processed secreted peptides is not known.
Alias Symbols: Saas
Protein Interaction Partner: STXBP5L,
Protein Size: 260 - 分子量
- 28 kDa
- 基因ID
- 246333
- NCBI登录号
- NM_019279, NP_062152
- UniProt
- Q9QXU9
-
You are here:
