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TLR8 抗体 (C-Term)

This anti-TLR8 antibody is a 兔 多克隆 antibody detecting TLR8 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 马, 绵羊 和 兔.
产品编号 ABIN2787921
发货至: 中国

Quick Overview for TLR8 抗体 (C-Term) (ABIN2787921)

抗原

See all TLR8 抗体
TLR8 (Toll-Like Receptor 8 (TLR8))

适用

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人, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 马, 绵羊, 兔

宿主

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克隆类型

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多克隆

标记

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This TLR8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against TLR8. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human TLR8
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1041 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TLR8 (Toll-Like Receptor 8 (TLR8))

    别名

    TLR8

    背景

    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
    Alias Symbols: CD288, MGC119599, MGC119600
    Protein Interaction Partner: BTK, UBC, MYD88,
    Protein Size: 1041

    分子量

    120 kDa

    基因ID

    51311

    NCBI登录号

    NM_138636, NP_619542

    UniProt

    Q9NR97

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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