TLR8 抗体 (C-Term)
Quick Overview for TLR8 抗体 (C-Term) (ABIN2787921)
抗原
See all TLR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against TLR8. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TLR8
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1041 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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别名
- TLR8
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背景
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Alias Symbols: CD288, MGC119599, MGC119600
Protein Interaction Partner: BTK, UBC, MYD88,
Protein Size: 1041 -
分子量
- 120 kDa
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基因ID
- 51311
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NCBI登录号
- NM_138636, NP_619542
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UniProt
- Q9NR97
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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