LKB1 抗体 (C-Term)
Quick Overview for LKB1 抗体 (C-Term) (ABIN2787893)
抗原
See all LKB1 (STK11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EAPVPIPPSP DTKDRWRSMT VVPYLEDLHG ADEDEDLFDI EDDIIYTQDF
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预测反应
- Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against STK11. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human STK11
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 433 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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别名
- STK11
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背景
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STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Alias Symbols: LKB1, PJS, hLKB1
Protein Interaction Partner: SPDEF, SIRT1, PRKAA1, ETV4, CDC37, HSP90AA1, TP63, Eif2b1, Ap2m1, SNRK, APP, TNIP2, SIK1, STRADA, STUB1, UBE2D2, MARK2, GSK3B, STRADB, CAB39, KIF23, USP11, SMARCC1, SMARCA4, LIMS1, HSPA1A, FKBP5, RPAP3, MARK4, UBC, CAB39L, WDR48, RPS6KB1, MOB4, MARK1, RPS
Protein Size: 433 -
分子量
- 49 kDa
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基因ID
- 6794
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NCBI登录号
- NM_000455, NP_000446
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UniProt
- Q15831
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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