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LKB1 抗体 (C-Term)

This anti-LKB1 antibody is a 兔 多克隆 antibody detecting LKB1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 斑马鱼, 犬, 马, 豚鼠 和 Cow.
产品编号 ABIN2787893
发货至: 中国
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Quick Overview for LKB1 抗体 (C-Term) (ABIN2787893)

抗原

See all LKB1 (STK11) 抗体
LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

适用

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人, 小鼠, 大鼠, 斑马鱼, 犬, 马, 豚鼠, Cow

宿主

  • 158
  • 10

克隆类型

  • 160
  • 8
多克隆

标记

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This LKB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    EAPVPIPPSP DTKDRWRSMT VVPYLEDLHG ADEDEDLFDI EDDIIYTQDF

    预测反应

    Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against STK11. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human STK11
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 433 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

    别名

    STK11

    背景

    STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
    Alias Symbols: LKB1, PJS, hLKB1
    Protein Interaction Partner: SPDEF, SIRT1, PRKAA1, ETV4, CDC37, HSP90AA1, TP63, Eif2b1, Ap2m1, SNRK, APP, TNIP2, SIK1, STRADA, STUB1, UBE2D2, MARK2, GSK3B, STRADB, CAB39, KIF23, USP11, SMARCC1, SMARCA4, LIMS1, HSPA1A, FKBP5, RPAP3, MARK4, UBC, CAB39L, WDR48, RPS6KB1, MOB4, MARK1, RPS
    Protein Size: 433

    分子量

    49 kDa

    基因ID

    6794

    NCBI登录号

    NM_000455, NP_000446

    UniProt

    Q15831

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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