Bcl-2 抗体 (Middle Region)
Quick Overview for Bcl-2 抗体 (Middle Region) (ABIN2787860)
抗原
See all Bcl-2 (BCL2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- ALSPVPPVVH LTLRQAGDDF SRRYRRDFAE MSSQLHLTPF TARGRFATVV
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
-
产品特性
- This is a rabbit polyclonal antibody against BCL2. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BCL2
-
-
anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibodyBCL2 适用: 人, 小鼠, 大鼠, 兔, Cow, 小鸡, Bacteria WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D1 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 适用: 人 WB, IHC, FACS, IF, StM, ISt 宿主: 小鼠 Monoclonal 100-D5 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal BCL2-2210R unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 适用: 人 WB, FACS, IP, IHC (p), ICC, IHC (fro) 宿主: 小鼠 Monoclonal Bcl-2-100 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)BCL2 适用: 人 ICFC 宿主: 小鼠 Monoclonal Bcl-2-100 PE
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 118-165) antibodyBCL2 适用: 人 WB, FACS, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 239 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
别名
- BCL2
-
背景
-
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Alias Symbols: Bcl-2, PPP1R50
Protein Interaction Partner: KEAP1, SQSTM1, BECN1, UBC, TP53BP2, BID, BCL2L1, BCL2, BAX, BAD, ATP2A3, NR4A1, KRAS, PPID, MDM4, BNIP3, BFAR, CDK1, BAG3, RAF1, IKBKG, TP53, PPP3CC, FKBP8, MAPK8, IKBKB, HSP90AA1, HIF1A, CRYAB, CHUK, PML, BRCA1, AMBRA1, ATG12, BIK, CISD2, MEX3D, PPP1CC,
Protein Size: 239 -
分子量
- 26 kDa
-
基因ID
- 596
-
NCBI登录号
- NM_000633, NP_000624
-
UniProt
- P10415
-
途径
- MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
-
