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COL1A2 抗体 (Middle Region)

COL1A2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 山羊, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787684
发货至: 中国
  • 抗原 See all COL1A2 抗体
    COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
    抗原表位
    • 13
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 犬, 兔, Cow, 山羊, 豚鼠, 马, 斑马鱼
    宿主
    • 58
    • 8
    • 5
    • 2
    克隆类型
    • 67
    • 6
    多克隆
    标记
    • 42
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This COL1A2 antibody is un-conjugated
    应用范围
    • 55
    • 31
    • 24
    • 16
    • 11
    • 9
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PGSVGPAGPR GPAGPSGPAG KDGRTGHPGT VGPAGIRGPQ GHQGPAGPPG
    预测反应
    Cow: 100%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against COL1A2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human COL1A2
    Top Product
    Discover our top product COL1A2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1366 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
    别名
    COL1A2 (COL1A2 产品)
    别名
    AA960264 antibody, AI325291 antibody, Col1a-2 antibody, Cola-2 antibody, Cola2 antibody, oim antibody, OI4 antibody, Gas-6 antibody, alpha2(I) antibody, hm:zehn2357 antibody, wu:fa98d05 antibody, wu:fa99g10 antibody, wu:fb04c08 antibody, wu:fb11d06 antibody, zehn2357 antibody, coagulation factor II, thrombin antibody, collagen, type I, alpha 2 antibody, collagen type I alpha 2 chain antibody, collagen type I alpha 2 L homeolog antibody, growth arrest specific 6 antibody, F2 antibody, Col1a2 antibody, col1a2.L antibody, COL1A2 antibody, Gas6 antibody, col1a2 antibody
    背景
    COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: OI4
    Protein Interaction Partner: UBQLN1, SGTA, PDGFB, PDGFA, COL1A1, PAN2, LIG4, MYOC, SHBG, UBC, MMP9, COL5A3, CD44, APP, P4HB, ITGA2B, TGFBI, LUM, BGN, VWF, ITGA2, SPARC, CD36, ITGB3, FN1, DCN, CD93,
    Protein Size: 1366
    分子量
    150 kDa
    基因ID
    1278
    NCBI登录号
    NM_000089, NP_000080
    UniProt
    P08123
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