RIC8A 抗体 (N-Term)
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- 抗原 See all RIC8A 抗体
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 马, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIC8A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KLTERVGLYR ERSFPHDVQF FDLRLLFLLT ALRTDVRQQL FQELKGVRLL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RIC8A. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RIC8A
- Top Product
- Discover our top product RIC8A Primary Antibody
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anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 462-534) antibody
RIC8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyRIC8A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyVerified RIC8A 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 143-192) antibodyRIC8A 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 537 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
- 别名
- RIC8A (RIC8A 产品)
- 别名
- RIC8 antibody, AI114950 antibody, RIC-8 antibody, Ric8a antibody, Ric-8A antibody, Ric8 antibody, ric-8 antibody, ric8 antibody, synembryn antibody, xtric-8 antibody, zgc:92294 antibody, Syn antibody, ric8a antibody, ric8ab antibody, CG15797 antibody, DmRic8 antibody, Dmel\\CG15797 antibody, Ric-8 antibody, l(1)G0397 antibody, ric-8a antibody, ricc8aa antibody, fj97c10 antibody, synbl antibody, wu:fj97c10 antibody, RIC8 guanine nucleotide exchange factor A antibody, microRNA 6743 antibody, synembryn-A antibody, RIC8 guanine nucleotide exchange factor A L homeolog antibody, CG15797 gene product from transcript CG15797-RB antibody, synembryn antibody, RIC8 guanine nucleotide exchange factor A S homeolog antibody, Synembryn antibody, RIC8 guanine nucleotide exchange factor B antibody, RIC8A antibody, Ric8a antibody, ric8a antibody, MIR6743 antibody, Tsp_08768 antibody, ric8a.L antibody, LOC411841 antibody, ric8a.S antibody, ric-8 antibody, ric8b antibody
- 背景
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RIC8A is a guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins.RIC8A is able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP.RIC8A is involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. RIC8A also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Alias Symbols: MGC104517, MGC131931, MGC148073, MGC148074, RIC8, synembryn
Protein Interaction Partner: NECAB2, UBQLN1, RABAC1, UBC, EFEMP1, SDCBP, NUTM1, SARNP, WDR61, DPP7, PAPSS2, EZR, UBA1, RPL38, PYGB, PLCG1, MC1R, APEX1, GNAQ, XPO1, GNAI1, UBQLN4, ZNF585B, RIC8A, MAPK8IP3, GNA13, TERF1, GNAI3, GNAI2, GNAS, GNAO1, TUBB2A,
Protein Size: 537 - 分子量
- 60 kDa
- 基因ID
- 60626
- NCBI登录号
- NM_021932, NP_068751
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
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