RALB 抗体 (Middle Region)
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- 抗原 See all RALB (Ralb) 抗体
- RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 山羊, 豚鼠, 马, 兔, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RALB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EHESFTATAE FREQILRVKS EEDKIPLLVV GNKSDLEERR QVPVDEARGK
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Ralb. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Ralb
- Top Product
- Discover our top product Ralb Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 206 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))
- 别名
- Ralb (Ralb 产品)
- 别名
- dRalb antibody, 5730472O18Rik antibody, Ral B antibody, ralb antibody, xralb antibody, zgc:100801 antibody, KRAS2 antibody, k-ras antibody, RAS like proto-oncogene B antibody, v-ral simian leukemia viral oncogene B antibody, v-ral simian leukemia viral oncogene homolog B L homeolog antibody, v-ral simian leukemia viral oncogene homolog Ba (ras related) antibody, v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) antibody, RALB antibody, Ralb antibody, ralb.L antibody, ralba antibody, ralb antibody
- 背景
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Ralb is a multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Ralb accomplishes its multiple functions by interacting with distinct downstream effectors. It acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. It is required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Ralb plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. It is required for suppression of apoptosis.
Alias Symbols: 5730472O18Rik
Protein Interaction Partner: Rgl3,
Protein Size: 206 - 分子量
- 23 kDa
- 基因ID
- 64143
- NCBI登录号
- NM_022327, NP_071722
- UniProt
- Q9JIW9
- 途径
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events
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