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RALB 抗体 (Middle Region)

Ralb 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 山羊, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786741
发货至: 中国
  • 抗原 See all RALB (Ralb) 抗体
    RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 37
    • 28
    • 17
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 山羊, 豚鼠, 马, 兔, Pig
    宿主
    • 28
    • 7
    • 2
    克隆类型
    • 30
    • 7
    多克隆
    标记
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RALB antibody is un-conjugated
    应用范围
    • 23
    • 10
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    EHESFTATAE FREQILRVKS EEDKIPLLVV GNKSDLEERR QVPVDEARGK
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against Ralb. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Ralb
    Top Product
    Discover our top product Ralb Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 206 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))
    别名
    Ralb (Ralb 产品)
    别名
    dRalb antibody, 5730472O18Rik antibody, Ral B antibody, ralb antibody, xralb antibody, zgc:100801 antibody, KRAS2 antibody, k-ras antibody, RAS like proto-oncogene B antibody, v-ral simian leukemia viral oncogene B antibody, v-ral simian leukemia viral oncogene homolog B L homeolog antibody, v-ral simian leukemia viral oncogene homolog Ba (ras related) antibody, v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) antibody, RALB antibody, Ralb antibody, ralb.L antibody, ralba antibody, ralb antibody
    背景
    Ralb is a multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Ralb accomplishes its multiple functions by interacting with distinct downstream effectors. It acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. It is required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Ralb plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. It is required for suppression of apoptosis.
    Alias Symbols: 5730472O18Rik
    Protein Interaction Partner: Rgl3,
    Protein Size: 206
    分子量
    23 kDa
    基因ID
    64143
    NCBI登录号
    NM_022327, NP_071722
    UniProt
    Q9JIW9
    途径
    Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events
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