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PSME2 抗体 (Middle Region)

PSME2 适用: 人, 小鼠, 大鼠, 犬, 马, 斑马鱼, Cow, 豚鼠, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786731
发货至: 中国
  • 抗原 See all PSME2 抗体
    PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
    抗原表位
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 20
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, 犬, 马, 斑马鱼, Cow, 豚鼠, 兔, 绵羊
    宿主
    • 39
    • 6
    • 1
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSME2 antibody is un-conjugated
    应用范围
    • 35
    • 24
    • 19
    • 13
    • 5
    • 4
    • 3
    • 2
    Western Blotting (WB)
    序列
    SKETHVMDYR ALVHERDEAA YGELRAMVLD LRAFYAELYH IISSNLEKIV
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against PSME2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PSME2
    Top Product
    Discover our top product PSME2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 239 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
    别名
    PSME2 (PSME2 产品)
    别名
    unp309 antibody, PA28B antibody, PA28beta antibody, REGbeta antibody, AA589371 antibody, AI788882 antibody, PA28b antibody, proteasome activator subunit 2 antibody, proteasome (prosome, macropain) activator subunit 2 (PA28 beta) antibody, psme2 antibody, PSME2 antibody, Psme2 antibody
    背景
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.
    Alias Symbols: PA28B, PA28beta, REGbeta
    Protein Interaction Partner: NAA10, PSMD14, SHFM1, UBC, PSME2, PSME1, PARK2, BAG3, NHLH1, MYOD1, EPHA2, CFTR, DDTL, TNN, CAP1, PTMA, PSMD7, PSMD2, PSMD1, PSMC5, PSMC4, PSMC2, PSMB5, PSMB3, PSMB1, PSMA6, PSMA5, PSMA3, PSMA2, PSMA1, GARS, APP, PSMC1, PSMD6, PSMB10, PSMB9, PSMB8, PSMB7,
    Protein Size: 239
    分子量
    27 kDa
    基因ID
    5721
    NCBI登录号
    NM_002818, NP_002809
    UniProt
    Q9UL46
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
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