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IL-15 抗体 (N-Term)

IL15 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊, 豚鼠, Pig, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN406559
发货至: 中国
  • 抗原 See all IL-15 (IL15) 抗体
    IL-15 (IL15) (Interleukin 15 (IL15))
    抗原表位
    • 38
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 57
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    • 10
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    • 2
    • 2
    • 1
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    人, 小鼠, 大鼠, Cow, 兔, 绵羊, 豚鼠, Pig, 马, 犬
    宿主
    • 69
    • 20
    • 4
    • 3
    • 3
    • 1
    克隆类型
    • 78
    • 22
    多克隆
    标记
    • 61
    • 18
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This IL-15 antibody is un-conjugated
    应用范围
    • 71
    • 36
    • 35
    • 18
    • 16
    • 10
    • 10
    • 9
    • 8
    • 6
    • 5
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    Western Blotting (WB)
    序列
    RISKPHLRSI SIQCYLCLLL NSHFLTEAGI HVFILGCFSA GLPKTEANWV
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against IL15. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human IL15
    Top Product
    Discover our top product IL15 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 162 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IL-15 (IL15) (Interleukin 15 (IL15))
    别名
    IL15 (IL15 产品)
    别名
    IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
    背景
    IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
    Alias Symbols: IL-15, MGC9721
    Protein Interaction Partner: ZNRD1, TRAF3, STAT5B, APP, IL15RA, IL2RG, IL2RB,
    Protein Size: 162
    分子量
    13 kDa
    基因ID
    3600
    NCBI登录号
    NM_172174, NP_751914
    UniProt
    P40933
    途径
    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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