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DAAM1 抗体 (Middle Region)

DAAM1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786070
发货至: 中国
  • 抗原 See all DAAM1 抗体
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    抗原表位
    • 14
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 59
    • 11
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬
    宿主
    • 55
    • 4
    克隆类型
    • 56
    • 3
    多克隆
    标记
    • 23
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAAM1 antibody is un-conjugated
    应用范围
    • 52
    • 44
    • 40
    • 13
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GNTVQYWLLL DRIIQQIVIQ NDKGQDPDST PLENFNIKNV VRMLVNENEV
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against DAAM1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DAAM1
    Top Product
    Discover our top product DAAM1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1078 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    别名
    DAAM1 (DAAM1 产品)
    别名
    1700066F09Rik antibody, 2310028E21Rik antibody, AI503486 antibody, E130308H01 antibody, mKIAA0666 antibody, daam-1 antibody, xdaam1 antibody, daam1 antibody, DAAM1 antibody, DKFZp468D0524 antibody, daam1l antibody, fc83b10 antibody, si:ch211-87i20.1 antibody, wu:fc83b10 antibody, dishevelled associated activator of morphogenesis 1 antibody, dishevelled associated activator of morphogenesis 1 S homeolog antibody, dishevelled associated activator of morphogenesis 1a antibody, dishevelled associated activator of morphogenesis 1b antibody, DAAM1 antibody, Daam1 antibody, daam1.S antibody, daam1a antibody, daam1 antibody, daam1b antibody
    背景
    Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
    Alias Symbols: FLJ41657, KIAA0666
    Protein Interaction Partner: UBC, PRPF40A, B3GALT4, AMBP, MAP3K7, DVL2, DVL1, RHOA,
    Protein Size: 1078
    分子量
    123 kDa
    基因ID
    23002
    NCBI登录号
    NM_014992, NP_055807
    UniProt
    Q9Y4D1
    途径
    WNT signaling
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