DAAM1 抗体 (AA 400-500)
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北京 101111
Quick Overview for DAAM1 抗体 (AA 400-500) (ABIN7228144)
抗原
See all DAAM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-500
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原理
- Rabbit Anti-DAAM1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DAAM1
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human DAAM1 protein at AA range: 400-500
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亚型
- IgG
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anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 1-110) antibody
DAAM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D3 unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 1-110) antibodyDAAM1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H3 unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 341-370), (N-Term) antibodyDAAM1 适用: 人, Hamster WB, IHC (p), FACS 宿主: 兔 Polyclonal RB15348 unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) antibodyDAAM1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 1034-1063), (C-Term) antibodyDAAM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10612 unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 1-110) antibodyDAAM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 396-445) antibodyDAAM1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) antibodyDAAM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (N-Term) antibodyDAAM1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (C-Term), (N-Term) antibodyDAAM1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
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别名
- DAAM1
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背景
- Disheveled-associated activator of morphogenesis 1Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by DAAM1 contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by DAAM1 is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.
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分子量
- 123kD
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基因ID
- 23002
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UniProt
- Q9Y4D1
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途径
- WNT signaling
抗原
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