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SESN1 抗体 (Middle Region)

SESN1 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786032
发货至: 中国
  • 抗原 See all SESN1 抗体
    SESN1 (Sestrin 1 (SESN1))
    抗原表位
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 49
    • 31
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔, 斑马鱼
    宿主
    • 47
    • 3
    克隆类型
    • 49
    • 1
    多克隆
    标记
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SESN1 antibody is un-conjugated
    应用范围
    • 40
    • 17
    • 16
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    KWLNGLENAP QKLQNLGELN KVLAHRPWLI TKEHIEGLLK AEEHSWSLAE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against SESN1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Human SESN1
    Top Product
    Discover our top product SESN1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SESN1 (Sestrin 1 (SESN1))
    别名
    SESN1 (SESN1 产品)
    别名
    zgc:91970 antibody, sestrin-1 antibody, SESN1 antibody, XPA26 antibody, pa26 antibody, sest1 antibody, PA26 antibody, SEST1 antibody, 1110002G11Rik antibody, AU044290 antibody, Pa26 antibody, Sest1 antibody, sesn1-A antibody, sestrin 1 antibody, sestrin 1 L homeolog antibody, SESN1 antibody, sesn1 antibody, Sesn1 antibody, sesn1.L antibody
    背景
    This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Alias Symbols: PA26, SEST1
    Protein Interaction Partner: UBC, RBX1, KEAP1, SQSTM1, PRDX1,
    Protein Size: 551
    分子量
    64 kDa
    基因ID
    27244
    NCBI登录号
    NM_014454, NP_055269
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