Fgr 抗体 (Middle Region)
Quick Overview for Fgr 抗体 (Middle Region) (ABIN2785753)
抗原
See all Fgr (FGR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- CPPGCPASLY EAMEQTWRLD PEERPTFEYL QSFLEDYFTS AEPQYQPGDQ
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Zebrafish: 83%
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产品特性
- This is a rabbit polyclonal antibody against FGR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FGR
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anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-90) antibody
FGR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G10 unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 3-33), (N-Term) antibodyFGR 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3095 unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 11-72) antibodyFGR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) antibodyFGR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 6G2 unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 11-40), (N-Term) antibodyFGR 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (C-Term) antibodyVerified FGR 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-529) antibodyFGR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-529) antibodyFGR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (Internal Region) antibodyFGR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-100) antibodyFGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 529 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
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别名
- FGR
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背景
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This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: FLJ43153, MGC75096, SRC2, c-fgr, c-src2, p55c-fgr, p58c-fgr, p55-Fgr, p58-Fgr
Protein Interaction Partner: IKBKG, STAT3, HSP90AA1, ERBB2, NR1I2, UBC, DOK1, KHDRBS1, SYK, SH3KBP1, FASLG, INPP5D, SLAMF1, VDR, HCLS1, CCR3, DAB2, PTK2, CD24, WAS, SRC, CBL, FGR, SNCA, YWHAQ, CSK, ARRB1, NCOA6,
Protein Size: 529 -
分子量
- 59 kDa
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基因ID
- 2268
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NCBI登录号
- NM_001042729, NP_001036194
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UniProt
- P09769
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途径
- Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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