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IL1A 抗体 (N-Term)

Name: IL1A 抗体 (N-Term)
SKU: ABIN2785653
Availability: OutOfStock

IL1A 适用: 人, 小鼠, 大鼠, 马, 山羊, 犬, Cow, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-IL1A Antibody Titration: 0. (IL1A 抗体 (N-Term))

1 image

(2 references)

产品编号 ABIN2785653

发货至: 中国

Datasheet as PDF

抗原 See all IL1A 抗体

IL1A (Interleukin 1 alpha (IL1A))
抗原表位
26

16

10

7

7

7

5

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
107

48

39

11

9

9

8

8

7

5

5

2

1
人, 小鼠, 大鼠, 马, 山羊, 犬, Cow, 绵羊
宿主
142

38

10

5

3

2

1
兔
Compatible Secondaries
克隆类型
157

42
多克隆
标记
103

46

18

11

6

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This IL1A antibody is un-conjugated
应用范围
146

98

65

27

26

24

18

12

10

9

9

7

4

3

2

2

2

1

1

1

1
Western Blotting (WB)

序列

VSYGPLHEGC MDQSVSLSIS ETSKTSKLTF KESMVVVATN GKVLKKRRLS

预测反应

Cow: 92%, Dog: 85%, Goat: 85%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 79%, Sheep: 85%

产品特性

This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human IL1A

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anti-Interleukin 1 alpha (IL1A) (N-Term) antibody
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anti-Interleukin 1 alpha (IL1A) (AA 151-220) antibody
IL1A 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 271 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: "Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-?B p65 protein." in: Cellular microbiology, Vol. 15, Issue 3, pp. 474-85, (2013) (PubMed).

Zheng, Humphry, Maguire, Bennett, Clarke: "Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1?, controlling necrosis-induced sterile inflammation." in: Immunity, Vol. 38, Issue 2, pp. 285-95, (2013) (PubMed).
抗原

IL1A (Interleukin 1 alpha (IL1A))

别名

IL1A (IL1A 产品)

别名

IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody

背景

The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IL-1A, IL1, IL1-ALPHA, IL1F1
Protein Interaction Partner: HFI1, AHC1, GCN5, SPT7, ADA2, NGG1, SPT8, HAX1, NFKBIE, IL1RAP, NDN, S100A13, IL1R2, IL1R1, IL1A, CAPN1,
Protein Size: 271

分子量

18 kDa

基因ID

3552

NCBI登录号

NM_000575, NP_000566

UniProt

P01583

途径

NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints