我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

IL1A 抗体 (N-Term)

Cited in 2+ publications. The 兔多克隆 anti-IL1A antibody (ABIN2785653) specifically detects IL1A in WB. The antibody is reactive with 人, 小鼠, 大鼠, 山羊, 马, 犬, Cow 和绵羊 samples.

1 image

(2 references)

产品编号 ABIN2785653

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL1A 抗体 (N-Term) (ABIN2785653)

抗原

See all IL1A 抗体

IL1A (Interleukin 1 alpha (IL1A))

适用

人, 小鼠, 大鼠, 山羊, 马, 犬, Cow, 绵羊

宿主

兔

克隆类型

多克隆

标记

This IL1A antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product IL1A Primary Antibody

抗原表位
27

16

7

7

6

5

4

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

序列

VSYGPLHEGC MDQSVSLSIS ETSKTSKLTF KESMVVVATN GKVLKKRRLS

预测反应

Cow: 92%, Dog: 85%, Goat: 85%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 79%, Sheep: 85%

产品特性

This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human IL1A
anti-Interleukin 1 alpha (IL1A) (AA 172-271) antibody
IL1A 适用: 人 WB, IP, ELISA, IF 宿主: 小鼠 Monoclonal 4F9 unconjugated

anti-Interleukin 1 alpha (IL1A) antibody
IL1A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6G4A5 unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 177-206) antibody
IL1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21521 unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 113-271) antibody
IL1A 适用: 人 WB 宿主: 小鼠 Monoclonal 3# unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 112-271) antibody
IL1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 90-268) antibody
IL1A 适用: 山羊 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 177-206) antibody
IL1A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 115-270) antibody
IL1A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated

anti-Interleukin 1 alpha (IL1A) (AA 113-271) antibody
IL1A 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Interleukin 1 alpha (IL1A) (N-Term) antibody
IL1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 271 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: "Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-?B p65 protein." in: Cellular microbiology, Vol. 15, Issue 3, pp. 474-85, (2013) (PubMed).

Zheng, Humphry, Maguire, Bennett, Clarke: "Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1?, controlling necrosis-induced sterile inflammation." in: Immunity, Vol. 38, Issue 2, pp. 285-95, (2013) (PubMed).
抗原

IL1A (Interleukin 1 alpha (IL1A))

别名

IL1A

背景

The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IL-1A, IL1, IL1-ALPHA, IL1F1
Protein Interaction Partner: HFI1, AHC1, GCN5, SPT7, ADA2, NGG1, SPT8, HAX1, NFKBIE, IL1RAP, NDN, S100A13, IL1R2, IL1R1, IL1A, CAPN1,
Protein Size: 271

分子量

18 kDa

基因ID

3552

NCBI登录号

NM_000575, NP_000566

UniProt

P01583

途径

NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints