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FBXO31 抗体 (Middle Region)

FBXO31 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785570
发货至: 中国
  • 抗原 See all FBXO31 抗体
    FBXO31 (F-Box Protein 31 (FBXO31))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 40
    • 19
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 34
    • 6
    克隆类型
    • 36
    • 4
    多克隆
    标记
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO31 antibody is un-conjugated
    应用范围
    • 37
    • 18
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against FBXO31. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
    Top Product
    Discover our top product FBXO31 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 367 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FBXO31 (F-Box Protein 31 (FBXO31))
    别名
    FBXO31 (FBXO31 产品)
    别名
    1110003O08Rik antibody, 2310046N15Rik antibody, Fbx14 antibody, Fbxo14 antibody, FBX14 antibody, FBXO14 antibody, Fbx31 antibody, pp2386 antibody, RGD1561069 antibody, fbx14 antibody, fbx31 antibody, fbxo14 antibody, fbxo31 antibody, F-box protein 31 antibody, F-box protein 31 S homeolog antibody, F-box protein 31 L homeolog antibody, Fbxo31 antibody, FBXO31 antibody, fbxo31 antibody, fbxo31.S antibody, fbxo31.L antibody
    背景
    FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
    Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
    Protein Interaction Partner: CDT1, UBE2L6, UBE2D1, CCND1, CUL1, MAP2K6, PARD6A, SKP1, COPS5, RBX1,
    Protein Size: 367
    分子量
    40 kDa
    基因ID
    79791
    NCBI登录号
    NM_024735, NP_079011
    UniProt
    Q5XUX0
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