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- 抗原 See all HFE2 抗体
- HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HFE2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SSLSIQTANP GNHVEIQAAY IGTTIIIRQT AGQLSFSIKV AEDVAMAFSA
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against HFE2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HFE2
- Top Product
- Discover our top product HFE2 Primary Antibody
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anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 41-386) antibody
HFE2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 93-173) antibodyHFE2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 93-173) antibodyHFE2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 234-416) antibodyHFE2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 29-401) antibodyHFE2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A6 unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 1-313) antibodyHFE2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 29-401) antibodyHFE2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 234-416) antibodyHFE2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 36-200) antibodyHFE2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (AA 34-393) antibodyHFE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 200 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
- 别名
- HFE2 (HFE2 产品)
- 别名
- HFE2A antibody, HJV antibody, JH antibody, RGMC antibody, HFE2 antibody, DKFZp468F2322 antibody, 2310035L15Rik antibody, 5230400G09Rik antibody, AI414844 antibody, AI789733 antibody, DL-M antibody, Rgmc antibody, hemojuvelin antibody, RGMr antibody, hjv antibody, id:ibd3464 antibody, wu:fb38f10 antibody, zgc:136698 antibody, hemochromatosis type 2 (juvenile) antibody, hemochromatosis type 2 antibody, HFE2 antibody, Hfe2 antibody, hfe2 antibody
- 背景
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The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.
Alias Symbols: HFE2A, HJV, JH, MGC23953, RGMC
Protein Size: 200 - 分子量
- 21 kDa
- 基因ID
- 148738
- NCBI登录号
- NM_202004, NP_973733
- UniProt
- Q6ZVN8
- 途径
- Transition Metal Ion Homeostasis
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