EGLN3 抗体 (C-Term)
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- 抗原 See all EGLN3 抗体
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EGLN3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FWSDRRNPHE VQPSYATRYA MTVWYFDAEE RAEAKKKFRN LTRKTESALT
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 77%, Zebrafish: 75%
- 产品特性
- This is a rabbit polyclonal antibody against EGLN3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EGLN3
- Top Product
- Discover our top product EGLN3 Primary Antibody
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anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-120) antibody
EGLN3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-239) antibodyEGLN3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-120) antibodyEGLN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 2-239) antibodyEGLN3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) antibodyEGLN3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-239) antibodyEGLN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 94-193) antibodyEGLN3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (Internal Region) antibodyVerified EGLN3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 50-100) antibodyEGLN3 适用: 人, 大鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (C-Term) antibodyEGLN3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴, 豚鼠, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 239 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
- 别名
- EGLN3 (EGLN3 产品)
- 别名
- zgc:77019 antibody, wu:fj78a08 antibody, EGLN3 antibody, phd3 antibody, PHD-3 antibody, PHD3 antibody, SM-20 antibody, 2610021G09Rik antibody, AI505553 antibody, AI648162 antibody, Hif-p4h-3 antibody, Phd3 antibody, HIFP4H3 antibody, HIFPH3 antibody, egl-9 family hypoxia-inducible factor 3 antibody, egl-9 family hypoxia inducible factor 3 antibody, egl-9 family hypoxia-inducible factor 3 L homeolog antibody, egln3 antibody, EGLN3 antibody, egln3.L antibody, Egln3 antibody
- 背景
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EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. EGLN3 functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. EGLN3 promotes cell death through a caspase-dependent mechanism.
Alias Symbols: FLJ21620, HIFPH3, MGC125998, MGC125999, PHD3
Protein Interaction Partner: FOXJ2, SERTAD1, NCAPH2, EFHC2, ABI2, SIAH2, REL, HIF1A, TTC23L, SQSTM1, HEXIM1, IKBKG, IKBKB, CHUK, MAPK7, MAPK6, MAPK1, PKM, EPAS1, UBD, MAGEA11, UBC, ATF4, WTIP, AJUBA, LIMD1, SPRY2, ADRB2, PRPF19, Myog, EGLN3, EGLN2, EGLN1, OS9, HIF3A, WDR83,
Protein Size: 239 - 分子量
- 27 kDa
- 基因ID
- 112399
- NCBI登录号
- NM_022073, NP_071356
- UniProt
- Q9H6Z9
- 途径
- Positive Regulation of Endopeptidase Activity
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