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CYP3A4 抗体 (Middle Region)

CYP3A4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 山羊, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784528
发货至: 中国
  • 抗原 See all CYP3A4 抗体
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    抗原表位
    • 16
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 88
    • 37
    • 35
    • 17
    • 15
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 山羊, 马
    宿主
    • 78
    • 9
    • 1
    克隆类型
    • 73
    • 15
    多克隆
    标记
    • 49
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CYP3A4 antibody is un-conjugated
    应用范围
    • 71
    • 24
    • 21
    • 20
    • 19
    • 16
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    MIPSYALHRD PKYWTEPEKF LPERFSKKNK DNIDPYIYTP FGSGPRNCIG
    预测反应
    Cow: 86%, Dog: 85%, Goat: 86%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 86%
    产品特性
    This is a rabbit polyclonal antibody against CYP3A4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CYP3A4
    Top Product
    Discover our top product CYP3A4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 503 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: "Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." in: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).

  • 抗原
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    别名
    CYP3A4 (CYP3A4 产品)
    别名
    CP33 antibody, CP34 antibody, CYP3A antibody, CYP3A3 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, HLP antibody, NF-25 antibody, P450C3 antibody, P450PCN1 antibody, MGC108372 antibody, CYP3A80 antibody, CYP3A4 antibody, CYP3A21 antibody, CYPIIIA21 antibody, CYP3A12 antibody, cytochrome P450 family 3 subfamily A member 4 antibody, cytochrome P450 family 3 subfamily A member 43 antibody, cytochrome P450 3A4 antibody, cytochrome P450, subfamily IIIA, polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, cytochrome P450, family 3, subfamily A, polypeptide 4 antibody, CYP3A4 antibody, CYP3A43 antibody, PTRG_01782 antibody, PTRG_06060 antibody, cyp3a4 antibody
    背景
    This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot
    Alias Symbols: CP33, CP34, CYP3A, CYP3A3, HLP, MGC126680, NF-25, P450C3, P450PCN1, CYPIIIA3, CYPIIIA4
    Protein Interaction Partner: UBC, PRKCA, PRKACA, PGRMC1, POR, GK, CYB5A, STUB1, AMFR, UGT2B7,
    Protein Size: 503
    分子量
    57 kDa
    基因ID
    1576
    NCBI登录号
    NM_017460, NP_059488
    UniProt
    P08684
    途径
    Steroid Hormone Biosynthesis
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