Retinoblastoma Binding Protein 8 抗体 (C-Term)
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Quick Overview for Retinoblastoma Binding Protein 8 抗体 (C-Term) (ABIN2784374)
抗原
See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ETVDMDCTLV SETVLLKMKK QEQKGEKSSN EERKMNDSLE DMFDRTTHEE
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预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 83%, Horse: 79%, Human: 100%, Pig: 100%, Rabbit: 100%
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产品特性
- This is a rabbit polyclonal antibody against RBBP8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RBBP8
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anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 452-747) antibody
RBBP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 1-300) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 126-331) antibodyRBBP8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) antibodyRBBP8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (Center) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) antibodyRBBP8 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro), EIA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 791-840) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 686-735) antibodyRBBP8 适用: 人, 猴, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (pSer326) antibodyRBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (pThr847) antibodyRBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 867 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Retinoblastoma Binding Protein 8 (RBBP8)
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别名
- RBBP8
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背景
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RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Alias Symbols: CTIP, RIM, JWDS, SAE2, SCKL2
Protein Interaction Partner: LMO4, PIN1, LMO1, MDM2, BRCA1, RBL1, TMEM54, PRRG4, RGS17, IKBKG, IGFBP7, EEF1A1, CTBP2, CLU, MAP2K4, RAF1, RBL2, PCNA, ZNF350, NBN, UIMC1, PALB2, BARD1, SPEN, RAD50, CTBP1, RB1, UBC, FXR2, RBBP8, IKZF1, LIMS1, SIAH2, SIAH1, LMO2, WDYHV1, ATM, TGIF2, IKZF
Protein Size: 867 -
分子量
- 98 kDa
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基因ID
- 5932
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NCBI登录号
- NM_203292, NP_976037
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UniProt
- A6NKN2
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途径
- Cell Division Cycle, DNA Damage Repair
抗原
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