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NOX1 抗体 (C-Term)

Name: NOX1 抗体 (C-Term)
SKU: ABIN2782754
Availability: OutOfStock

This anti-NOX1 antibody is a 兔多克隆 antibody detecting NOX1 in WB. Suitable for 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 斑马鱼和兔. This Primary Antibody has been cited in 2+ publications.

WB Suggested Anti-NOX1 Antibody Titration: 0. (NOX1 抗体 (C-Term))

Western Blotting (WB) image for anti-NADPH Oxidase 1 (NOX1) (C-Term) antibody (ABIN2782754) (NOX1 抗体 (C-Term))

NOX1 antibody - C-terminal region validated by WB using Epithelial Colorectal Adenocarcinoma CaCO2 at 1:10. (NOX1 抗体 (C-Term))

Host: Rabbit Target Name: NOX1 Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml (NOX1 抗体 (C-Term))

Host: Rabbit Target Name: NOX1 Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 1ug/ml (NOX1 抗体 (C-Term))

5 images

(2 references)

产品编号 ABIN2782754

发货至: 中国

Datasheet as PDF

Quick Overview for NOX1 抗体 (C-Term) (ABIN2782754)

抗原

See all NOX1 抗体

NOX1 (NADPH Oxidase 1 (NOX1))

适用

人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔

宿主

兔

克隆类型

多克隆

标记

This NOX1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product NOX1 Primary Antibody

抗原表位
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C-Term

序列

STIATSHPKS VVGVFLCGPR TLAKSLRKCC HRYSSLDPRK VQFYFNKENF

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

产品特性

This is a rabbit polyclonal antibody against NOX1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human NOX1
anti-NADPH Oxidase 1 (NOX1) antibody
NOX1 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 235-488) antibody
NOX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (Internal Region) antibody
Verified NOX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (C-Term) antibody
NOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 291-544) antibody
NOX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 418-564) antibody
NOX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 425-515) antibody
NOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 200-300) antibody
NOX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 354-374), (Middle Region) antibody
NOX1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-NADPH Oxidase 1 (NOX1) (AA 417-431), (Middle Region) antibody
NOX1 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 564 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Rayegan, Dehpour, Sharifi: "Studying neuroprotective effect of Atorvastatin as a small molecule drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase." in: Metabolic brain disease, Vol. 32, Issue 1, pp. 41-49, (2016) (PubMed).

Kuwano, Kawahara, Yamamoto, Teshima-Kondo, Tominaga, Masuda, Kishi, Morita, Rokutan: "Interferon-gamma activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells." in: American journal of physiology. Cell physiology, Vol. 290, Issue 2, pp. C433-43, (2006) (PubMed).
抗原

NOX1 (NADPH Oxidase 1 (NOX1))

别名

NOX1

背景

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism.
Alias Symbols: GP91-2, MOX1, NOH-1, NOH1
Protein Interaction Partner: NOXA1, CYBA,
Protein Size: 564

分子量

65 kDa

基因ID

27035

NCBI登录号

NM_007052, NP_008983

UniProt

Q9Y5S8

途径

Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport