HBEGF 抗体 (N-Term)
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北京 101111
Quick Overview for HBEGF 抗体 (N-Term) (ABIN2782149)
抗原
See all HBEGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FLAAVLSALV TGESLERLRR GLAAGTSNPD PPTVSTDQLL PLGGGRDRKV
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HBEGF. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human HBEGF
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anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 51-150) antibody
HBEGF 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (EGF Like Domain) antibody (Biotin)HBEGF 适用: 人 WB, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 4G10 Biotin
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (Bound), (EGF Like Domain), (Soluble) antibodyHBEGF 适用: 人 WB, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 20-160) antibodyHBEGF 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) antibodyHBEGF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (N-Term) antibodyHBEGF 适用: 人, 小鼠, 大鼠, Cow, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
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别名
- HBEGF
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背景
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HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.
Alias Symbols: DTR, DTS, DTSF, HEGFL
Protein Interaction Partner: Bag1, BCL6, ZBTB16, CD82, NRD1, LTBP3, ERBB4, MMP7, CD9, FBLN1, EGFR, HBEGF, CD44,
Protein Size: 208 -
分子量
- 22 kDa
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基因ID
- 1839
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NCBI登录号
- NM_001945, NP_001936
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UniProt
- Q99075
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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