ATP2B4 抗体 (Middle Region)
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- 抗原 See all ATP2B4 抗体
- ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP2B4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FAGEKFFDID SGRKAPLHSP PSQHYTIVFN TFVLMQLFNE INSRKIHGEK
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against ATP2B4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ATP2B4
- Top Product
- Discover our top product ATP2B4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1170 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))
- 别名
- ATP2B4 (ATP2B4 产品)
- 别名
- ATP2B2 antibody, MXRA1 antibody, PMCA4 antibody, PMCA4b antibody, PMCA4x antibody, atp2b2 antibody, atp2b3 antibody, mxra1 antibody, pmca4 antibody, pmca4b antibody, pmca4x antibody, zgc:152801 antibody, ATP2B4 antibody, ATP2B1 antibody, Pmca4 antibody, ATPase plasma membrane Ca2+ transporting 4 antibody, ATPase, Ca++ transporting, plasma membrane 4 L homeolog antibody, ATPase, Ca++ transporting, plasma membrane 4 antibody, ATP2B4 antibody, atp2b4.L antibody, atp2b4 antibody, Atp2b4 antibody
- 背景
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ATP2B4 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B4 is the plasma membrane calcium ATPase isoform 4.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ATP2B2, DKFZp686G08106, DKFZp686M088, MXRA1, PMCA4, PMCA4b, PMCA4x
Protein Interaction Partner: UBC, CDK7, ADRB2, ERBB2IP, RASSF1, DLG2, DLG4, DLG1, DLG3, CASK, SRC, NOS1, PPP3CA, CD22, PDZD11,
Protein Size: 1170 - 分子量
- 129 kDa
- 基因ID
- 493
- NCBI登录号
- NM_001001396, NP_001001396
- UniProt
- B1APW5
- 途径
- Ribonucleoside Biosynthetic Process
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