PTGIS 抗体 (Middle Region)
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- 抗原 See all PTGIS 抗体
- PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 斑马鱼, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTGIS antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EIYTDPEVFK YNRFLNPDGS EKKDFYKDGK RLKNYNMPWG AGHNHCLGRS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against PTGIS. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PTGIS
- Top Product
- Discover our top product PTGIS Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 500 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
- 别名
- PTGIS (PTGIS 产品)
- 别名
- CYP8 antibody, CYP8A1 antibody, PGIS antibody, PTGI antibody, Cyp8 antibody, Cyp8a1 antibody, Pgis antibody, ptgisl antibody, PTGIS antibody, prostaglandin I2 synthase antibody, prostaglandin I2 (prostacyclin) synthase antibody, prostacyclin synthase antibody, PTGIS antibody, Ptgis antibody, ptgis antibody, VDBG_06319 antibody
- 背景
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PTGIS is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CYP8, CYP8A1, MGC126858, MGC126860, PGIS, PTGI
Protein Interaction Partner: CAV1, PTGS2, PTGS1, APP,
Protein Size: 500 - 分子量
- 57 kDa
- 基因ID
- 5740
- NCBI登录号
- NM_000961, NP_000952
- UniProt
- Q16647
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