SLC6A5 antibody, Glyt2 antibody, prestin antibody, GLYT-2 antibody, GLYT2 antibody, HKPX3 antibody, NET1 antibody, solute carrier family 6 member 5 antibody, solute carrier family 6 (neurotransmitter transporter, glycine), member 5 antibody, SLC6A5 antibody, Slc6a5 antibody
背景
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia, a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. Alias Symbols: NET1, GLYT2, HKPX3, GLYT-2 Protein Size: 395