ABCA7 抗体 (Middle Region)
-
- 抗原 See all ABCA7 抗体
- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
-
抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ABCA7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM DEPTAGVDPA SRRGIWELLL
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Abca7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 2159 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models." in: Journal of Alzheimer's disease : JAD, Vol. 53, Issue 3, pp. 875-92, (2016) (PubMed).
: "
-
Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models." in: Journal of Alzheimer's disease : JAD, Vol. 53, Issue 3, pp. 875-92, (2016) (PubMed).
-
- 抗原
- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
- 别名
- Abca7 (ABCA7 产品)
- 别名
- ABCX antibody, Abc51 antibody, ABCA-SSN antibody, ABCA7 antibody, ATP-binding cassette, sub-family A (ABC1), member 7 antibody, ATP binding cassette subfamily A member 7 antibody, ATP-binding cassette sub-family A member 7 antibody, Abca7 antibody, ABCA7 antibody, LOC100088822 antibody
- 背景
-
Abca7 plays a role in phagocytosis by macrophages of apoptotic cells.Abca7 binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. Abca7 may also mediate cholesterol efflux. Abca7 may regulate cellular ceramide homeostasis during keratinocytes differentiation.
Alias Symbols: ABCX, Abc51
Protein Size: 2159 - 分子量
- 237 kDa
- 基因ID
- 27403
- NCBI登录号
- NM_013850, NP_038878
- UniProt
- Q91V24
-