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PCSK5 抗体 (Middle Region)

PCSK5 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781306
发货至: 中国
  • 抗原 See all PCSK5 抗体
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    抗原表位
    • 14
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔
    宿主
    • 36
    • 1
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCSK5 antibody is un-conjugated
    应用范围
    • 24
    • 20
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    CAGAGADGCI NCTEGYFMED GRCVQSCSIS YYFDHSSENG YKSCKKCDIS
    预测反应
    Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against PCSK5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PCSK5
    Top Product
    Discover our top product PCSK5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 913 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Szumska, Pieles, Essalmani, Bilski, Mesnard, Kaur, Franklyn, El Omari, Jefferis, Bentham, Taylor, Schneider, Arnold, Johnson, Tymowska-Lalanne, Stammers, Clarke, Neubauer, Morris, Brown, Shaw-Smith, Cama, Capra, Ragoussis, Constam, Seidah, Prat, Bhattacha: "VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5." in: Genes & development, Vol. 22, Issue 11, pp. 1465-77, (2008) (PubMed).

  • 抗原
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    别名
    PCSK5 (PCSK5 产品)
    别名
    PC5 antibody, PC6 antibody, PC6A antibody, SPC6 antibody, subtilase antibody, PC5/6A antibody, PC5A antibody, b2b1549Clo antibody, b2b585Clo antibody, Pc5 antibody, fur2 antibody, spc6 antibody, spc6A antibody, MGC98915 antibody, PCSK5 antibody, pc6 antibody, spc6a antibody, pcsk5 antibody, zgc:165659 antibody, proprotein convertase subtilisin/kexin type 5 antibody, proprotein convertase subtilisin/kexin type 5 S homeolog antibody, proprotein convertase subtilisin/kexin type 5b antibody, PCSK5 antibody, Pcsk5 antibody, pcsk5.S antibody, LOC528098 antibody, pcsk5 antibody, pcsk5b antibody
    背景
    PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PC5, PC6, PC6A, SPC6
    Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-7, LCE3C, KRTAP4-12, NUFIP2, GLRX3, STK16, MEOX2, KRTAP5-9, env, Hoxa1, ATN1, UBC, CACNA1A, APPBP2, AMH, REN, PTPRM, PMCH, ITGA6,
    Protein Size: 913
    分子量
    89 kDa
    基因ID
    5125
    NCBI登录号
    NM_006200, NP_006191
    UniProt
    Q92824
    途径
    Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones
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