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TARDBP 抗体 (N-Term)

Name: TARDBP 抗体 (N-Term)
SKU: ABIN2780848
Availability: OutOfStock

Cited in 1 publication. This anti-TARDBP antibody is a 兔多克隆 antibody detecting TARDBP in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马和豚鼠.

WB Suggested Anti-TARDBP Antibody Titration: 1. (TARDBP 抗体 (N-Term))

IHC

IHC

Host: Rabbit Target Name: TARDBP Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1. (TARDBP 抗体 (N-Term))

5 images

(1 reference)

产品编号 ABIN2780848

发货至: 中国

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Quick Overview for TARDBP 抗体 (N-Term) (ABIN2780848)

抗原

See all TARDBP 抗体

TARDBP (TAR DNA Binding Protein (TARDBP))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This TARDBP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product TARDBP Primary Antibody

抗原表位
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N-Term

序列

MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against TARDBP. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human TARDBP
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibody
TARDBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
TARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
TARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated

anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibody
TARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibody
TARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
KO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-396) antibody
TARDBP 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-261) antibody
TARDBP 适用: 人 WB, IHC, IF, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 414 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Estes, Boehringer, Zwick, Tang, Grigsby, Zarnescu: "Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS." in: Human molecular genetics, Vol. 20, Issue 12, pp. 2308-21, (2011) (PubMed).
抗原

TARDBP (TAR DNA Binding Protein (TARDBP))

别名

TARDBP

背景

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Alias Symbols: ALS10, TDP-43
Protein Interaction Partner: ZFAND2B, TARDBP, UBC, SUMO2, STAU1, SUMO3, RNF4, USP8, RBM45, RNF2, LSM6, UBE2E3, GNB2L1, MED6, RPA1, WWOX, RPA3, RPA2, PARK2, EED, BMI1, RBM39, BAG2, RPL23, DDX21, PRPF3, USP10, SART1, RPL14, H1FX, FUBP3, PABPC4, EIF4G3, EIF3I, EIF3H, EIF3C, EIF3B, EIF3A
Protein Size: 414

分子量

45 kDa

基因ID

23435

NCBI登录号

NM_007375, NP_031401

UniProt

Q13148

途径

Positive Regulation of Peptide Hormone Secretion