REST 抗体 (Middle Region)
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- 抗原 See all REST 抗体
- REST (RE1-Silencing Transcription Factor (REST))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This REST antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ANMGMALTND MYDLHELSKA ELAAPQLIML ANVALTGEAS GSCCDYLVGE
- 预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Rest. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product REST Primary Antibody
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anti-RE1-Silencing Transcription Factor (REST) (AA 401-450) antibody
REST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (Middle Region) antibodyREST 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 760-1060) antibodyREST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 250-350) antibodyREST 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 20-69) antibodyREST 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (C-Term) antibodyREST 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (Internal Region) antibodyVerified REST 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1082 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- REST (RE1-Silencing Transcription Factor (REST))
- 别名
- Rest (REST 产品)
- 别名
- NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
- 背景
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Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Alias Symbols: 2610008J04Rik, AA407358, MGC150099, NRSF
Protein Interaction Partner: L3mbtl2, Htt, Nanog, Sp3, Ewsr1, Nr0b1, Syt4, Calb1, Scn2a1, Bdnf, Ascl1,
Protein Size: 1082 - 分子量
- 118 kDa
- 基因ID
- 19712
- NCBI登录号
- NM_011263, NP_035393
- UniProt
- Q8VIG1
- 途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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