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RUNX2 抗体 (C-Term)

Name: RUNX2 抗体 (C-Term)
SKU: ABIN2780589
Availability: OutOfStock

This anti-RUNX2 antibody is a 兔多克隆 antibody detecting RUNX2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Pig 和兔. This Primary Antibody has been cited in 1 publication.

Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2 Gene Name: Anonymous Submitted by: (RUNX2 抗体 (C-Term))

WB Suggested Anti-RUNX2 Antibody Titration: 0. (RUNX2 抗体 (C-Term))

2 images

(1 reference)

产品编号 ABIN2780589

发货至: 中国

Datasheet as PDF

Quick Overview for RUNX2 抗体 (C-Term) (ABIN2780589)

抗原

See all RUNX2 抗体

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Pig, 兔

宿主

兔

克隆类型

多克隆

标记

This RUNX2 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product RUNX2 Primary Antibody

抗原表位
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1
C-Term

序列

TTTSNGSTLL NPNLPNQNDG VDADGSHSSS PTVLNSSGRM DESVWRPY

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 83%, Rat: 100%, Zebrafish: 92%

产品特性

This is a rabbit polyclonal antibody against RUNX2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human RUNX2
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibody
RUNX2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibody
RUNX2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibody
RUNX2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (Internal Region) antibody
RUNX2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) antibody
RUNX2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 1D2 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 507 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Wang, He, Liu, Liu, Zhou, Hao, Sun, Wang: "Synergistic effects of overexpression of BMP‑2 and TGF‑β3 on osteogenic differentiation of bone marrow mesenchymal stem cells." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5514-5520, (2016) (PubMed).
抗原

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

别名

RUNX2

背景

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.
Alias Symbols: AML3, CBFA1, CCD, CCD1, MGC120022, MGC120023, OSF2, PEA2aA, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1, OSF-2
Protein Interaction Partner: HDAC7, HDAC6, TP53, UBC, RB1, PML, HIF1A, SMURF1, SMAD1, SMURF2, HIVEP3, WWP1, FHL2, UBTF, SUV39H1, HDAC1, STAT3, SMAD3, RBM14, SOX9, NR0B2, EP300, HDAC5, HDAC4, HDAC3, CREBBP, XRCC5, HES1, XRCC6, BMPR1A, KAT2B, TLE1, YAP1, KAT6B, TAF1A, AXIN1, SMAD6, MAP
Protein Size: 507

分子量

55 kDa

基因ID

860

NCBI登录号

NM_004348, NP_004339