TIMELESS 抗体 (C-Term)
Quick Overview for TIMELESS 抗体 (C-Term) (ABIN2780562)
抗原
See all TIMELESS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EEEDAVGKEP LKAAPKKRQL LDSDEEQEED EGRNRAPELG APGIQKKKRY
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 90%, Rat: 100%, Sheep: 100%, Yeast: 91%
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产品特性
- This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TIMELESS
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anti-Timeless Homolog (TIMELESS) (AA 1-1208) antibody
TIMELESS 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1004-1131) antibodyTIMELESS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 290-339) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Pig, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1-1208) antibodyTIMELESS 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1109-1207) antibodyTIMELESS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人, 犬, Cow, 马, 绵羊, Pig, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (C-Term) antibodyTIMELESS 适用: 人, 大鼠, Cow, 马, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1208 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TIMELESS (Timeless Homolog (TIMELESS))
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别名
- TIMELESS
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背景
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The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Alias Symbols: TIM, TIM1, hTIM
Protein Interaction Partner: UBC, TUT1, TF, XRCC1, FKBP3, SP1, SUMO2, Tipin, Timeless, ZSCAN1, PCBD1, CRY1, PER2, PER1, CLSPN, PCNA, per, Clock, ATRIP, CRY2, CHEK1,
Protein Size: 1208 -
分子量
- 139 kDa
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基因ID
- 8914
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NCBI登录号
- NM_003920, NP_003911
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UniProt
- Q9UNS1
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途径
- Protein targeting to Nucleus, Photoperiodism
抗原
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