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TIMELESS 抗体 (N-Term)

The 兔 多克隆 anti-TIMELESS antibody is suitable to detect TIMELESS in samples from 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔 和 斑马鱼. It has been validated for WB.
产品编号 ABIN2780561
发货至: 中国
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Quick Overview for TIMELESS 抗体 (N-Term) (ABIN2780561)

抗原

See all TIMELESS 抗体
TIMELESS (Timeless Homolog (TIMELESS))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This TIMELESS antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human TIMELESS
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1208 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TIMELESS (Timeless Homolog (TIMELESS))

    别名

    TIMELESS

    背景

    The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
    Alias Symbols: TIM, TIM1, hTIM
    Protein Interaction Partner: UBC, TUT1, TF, XRCC1, FKBP3, SP1, SUMO2, Tipin, Timeless, ZSCAN1, PCBD1, CRY1, PER2, PER1, CLSPN, PCNA, per, Clock, ATRIP, CRY2, CHEK1,
    Protein Size: 1208

    分子量

    139 kDa

    基因ID

    8914

    NCBI登录号

    NM_003920, NP_003911

    UniProt

    Q9UNS1

    途径

    Protein targeting to Nucleus, Photoperiodism
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