Estrogen Receptor alpha 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Estrogen Receptor alpha 抗体 (N-Term) (ABIN501619)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- LERPLGEVYL DSSKPAVYNY PEGAAYEFNA AAAANAQVYG QTGLPYGPGS
-
预测反应
- Cow: 93%, Dog: 79%, Goat: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against ESR1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ESR1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 595 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
-
别名
- ESR1
-
背景
-
ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodi
Alias Symbols: DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
Protein Interaction Partner: SRC, DDX5, POLR2C, POLR2B, POLR2A, MSH2, TTC5, KAT5, NCOA2, BRCA1, MED24, UBC, PSMB9, MED1, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, ASCC1, TRRAP, PHB2, NCOR1, NCOA1, PIK3CA, IGF1R, HDAC1, NSD1, WIPI1, ESR1, ZNF131, RANBP9,
Protein Size: 595 -
分子量
- 66 kDa
-
基因ID
- 2099
-
NCBI登录号
- NM_000125, NP_000116
-
UniProt
- P03372
-
途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
-