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LEF1 抗体 (Middle Region)

The 兔 多克隆 anti-LEF1 antibody is suitable to detect LEF1 in samples from 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 兔, 山羊 和 Pig. It has been validated for WB.
产品编号 ABIN2779621
发货至: 中国
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Quick Overview for LEF1 抗体 (Middle Region) (ABIN2779621)

抗原

See all LEF1 抗体
LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 兔, 山羊, Pig

宿主

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克隆类型

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多克隆

标记

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This LEF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    ADIKSSLVNE SEIIPASNGH EVARQAQTSQ EPYHDKAREH PDDGKHPDGG

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against LEF1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human LEF1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 399 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

    别名

    LEF1

    背景

    Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1).
    Alias Symbols: DKFZp586H0919, FLJ46390, TCF1ALPHA, LEF-1, TCF10, TCF7L3
    Protein Interaction Partner: RNF138, UBC, RNF14, NLK, NARF, STAT5A, PITX2, CTNNB1, CDX1, DPYSL2, nrarp, FHIT, MITF, HINT1, TLE2, TLE1, SETD8, MYB, E2F1, HDAC1, ZBTB3, DACT1, DAZAP2, ALYREF, PIAS4, ALX4, SMAD3, SUMO2, EP300, SMAD1, SMAD2, SMAD4, KPNA1, KPNA2, UBTF, RUNX2, NOTCH1, RUVB
    Protein Size: 399

    分子量

    44 kDa

    基因ID

    51176

    NCBI登录号

    NM_016269, NP_057353

    UniProt

    Q9UJU2

    途径

    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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