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BCL2L1 抗体 (N-Term)

This anti-BCL2L1 antibody is a 兔 多克隆 antibody detecting BCL2L1 in WB. Suitable for 人, 小鼠, 大鼠, Pig, 绵羊, 犬, Cow, 兔, 马 和 豚鼠.
产品编号 ABIN2779336
发货至: 中国

Quick Overview for BCL2L1 抗体 (N-Term) (ABIN2779336)

抗原

See all BCL2L1 抗体
BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

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人, 小鼠, 大鼠, Pig, 绵羊, 犬, Cow, 兔, 马, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This BCL2L1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    N-Term

    序列

    SNRELVVDFL SYKLSQKGYS WSQFSDVEEN RTEAPEGTES EMETPSAING

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against BCL2L1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2L1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 233 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    别名

    BCL2L1

    背景

    BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
    Alias Symbols: BCL-XL/S, BCL2L, BCLX, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS, BCLXL, BCLXS, PPP1R52
    Protein Interaction Partner: BCL2L1, BCL2, BAX, BAD, BMF, BBC3, CASP8AP2, BECN1, UBC, TPT1, TP53BP2, ced-9, ced-4, PGAM5, CDKN2A, CASP1, BCL2L11, HRK, PMAIP1, BIK, BID, PARK2, PINK1, BAK1, RAD9A, AKT1, Mapk1, ATXN3, CLU, BCAP31, CRYAB, CRYAA, BFAR, PPP1CC, PPP1CA, ACTB, UBR1, METTL23
    Protein Size: 233

    分子量

    26 kDa

    基因ID

    598

    NCBI登录号

    NM_138578, NP_612815

    UniProt

    Q07817

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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