BAK1 抗体 (N-Term)
-
- 抗原 See all BAK1 抗体
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
-
抗原表位
- N-Term
-
适用
- 人, 马
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This BAK1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- ASGQGPGPPR QECGEPALPS ASEEQVAQDT EEVFRSYVFY RHQQEQEAEG
- 预测反应
- Horse: 80%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against BAK1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product BAK1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 211 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- 别名
- BAK1 (BAK1 产品)
- 别名
- BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
- 背景
-
BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Alias Symbols: BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
Protein Interaction Partner: BCL2L2, BCL2A1, BCL2L1, BMH1, NFKBIB, HSD17B4, TOMM7, ABCB10, TOMM40, TP53, BAX, MCL1, UBC, DBN1, ARHGDIA, MFN1, BCL2L10, VDAC1, ERN1, BID, BAK1, VDAC2, BCL2, HSPD1, FRYL, SRRM2, MYCBP2, AKAP13, ACTR2, KRT31, FBL, DFFA,
Protein Size: 211 - 分子量
- 23 kDa
- 基因ID
- 578
- NCBI登录号
- NM_001188, NP_001179
- UniProt
- Q16611
- 途径
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
-