BAK1 抗体 (N-Term)
Quick Overview for BAK1 抗体 (N-Term) (ABIN2779335)
抗原
See all BAK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ASGQGPGPPR QECGEPALPS ASEEQVAQDT EEVFRSYVFY RHQQEQEAEG
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预测反应
- Horse: 80%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against BAK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 211 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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别名
- BAK1
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背景
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BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Alias Symbols: BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
Protein Interaction Partner: BCL2L2, BCL2A1, BCL2L1, BMH1, NFKBIB, HSD17B4, TOMM7, ABCB10, TOMM40, TP53, BAX, MCL1, UBC, DBN1, ARHGDIA, MFN1, BCL2L10, VDAC1, ERN1, BID, BAK1, VDAC2, BCL2, HSPD1, FRYL, SRRM2, MYCBP2, AKAP13, ACTR2, KRT31, FBL, DFFA,
Protein Size: 211 -
分子量
- 23 kDa
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基因ID
- 578
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NCBI登录号
- NM_001188, NP_001179
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UniProt
- Q16611
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途径
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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