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BAK1 抗体 (N-Term)

This anti-BAK1 antibody is a 兔 多克隆 antibody detecting BAK1 in WB. Suitable for 人 和 马.
产品编号 ABIN2779335
发货至: 中国

Quick Overview for BAK1 抗体 (N-Term) (ABIN2779335)

抗原

See all BAK1 抗体
BAK1 (BCL2-Antagonist/killer 1 (BAK1))

适用

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人, 马

宿主

  • 70
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  • 2
  • 1

克隆类型

  • 61
  • 20
多克隆

标记

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  • 1
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This BAK1 antibody is un-conjugated

应用范围

  • 65
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  • 23
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Western Blotting (WB)
  • 抗原表位

    • 16
    • 12
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    • 1
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    N-Term

    序列

    ASGQGPGPPR QECGEPALPS ASEEQVAQDT EEVFRSYVFY RHQQEQEAEG

    预测反应

    Horse: 80%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against BAK1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 211 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BAK1 (BCL2-Antagonist/killer 1 (BAK1))

    别名

    BAK1

    背景

    BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
    Alias Symbols: BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
    Protein Interaction Partner: BCL2L2, BCL2A1, BCL2L1, BMH1, NFKBIB, HSD17B4, TOMM7, ABCB10, TOMM40, TP53, BAX, MCL1, UBC, DBN1, ARHGDIA, MFN1, BCL2L10, VDAC1, ERN1, BID, BAK1, VDAC2, BCL2, HSPD1, FRYL, SRRM2, MYCBP2, AKAP13, ACTR2, KRT31, FBL, DFFA,
    Protein Size: 211

    分子量

    23 kDa

    基因ID

    578

    NCBI登录号

    NM_001188, NP_001179

    UniProt

    Q16611

    途径

    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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