TAF15 抗体 (N-Term)
(2 references)-
- 抗原 See all TAF15 抗体
- TAF15 (TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAF15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TDSSYGQNYS GYSSYGQSQS GYSQSYGGYE NQKQSSYSQQ PYNNQGQQQN
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 77%
- 产品特性
- This is a rabbit polyclonal antibody against TAF15. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TAF15
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anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (Internal Region) antibody
TAF15 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (Center) antibodyTAF15 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (AA 93-206) antibodyTAF15 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) antibodyTAF15 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (AA 1-592) antibodyTAF15 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (AA 42-91) antibodyTAF15 适用: 人, 兔, 豚鼠, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (AA 1-280) antibodyTAF15 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (AA 1-592) antibodyTAF15 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (AA 122-171) antibodyTAF15 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) (Internal Region) antibodyTAF15 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 592 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Diagnostic and therapeutic potential of a human antibody cloned from a cancer patient that binds to a tumor-specific variant of transcription factor TAF15." in: Cancer research, Vol. 70, Issue 1, pp. 398-408, (2010) (PubMed).
: "Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src." in: FEBS letters, Vol. 564, Issue 1-2, pp. 188-98, (2004) (PubMed).
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: "Diagnostic and therapeutic potential of a human antibody cloned from a cancer patient that binds to a tumor-specific variant of transcription factor TAF15." in: Cancer research, Vol. 70, Issue 1, pp. 398-408, (2010) (PubMed).
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- 抗原
- TAF15 (TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))
- 别名
- TAF15 (TAF15 产品)
- 别名
- 2610111C21Rik antibody, 68kDa antibody, TAFII68 antibody, Taf2n antibody, Npl3 antibody, RBP56 antibody, TAF2N antibody, TATA-box binding protein associated factor 15 antibody, Taf15 antibody, TAF15 antibody
- 背景
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. Its gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.
Alias Symbols: Npl3, RBP56, TAF2N, TAFII68, hTAFII68
Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, EED, UBD, PRMT8, MED26, UBC, FUS, TPR, TPM2, DDB1, SCARB2, RNF168, TMED9, SAP30BP, NEDD8, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, YWHAZ, SIRT7, HIST2H4A, HIST1H3A, HIST2H2AC, CACNA1A,
Protein Size: 592 - 分子量
- 61 kDa
- 基因ID
- 8148
- NCBI登录号
- NM_139215, NP_631961
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