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SYNCRIP 抗体 (Middle Region)

SYNCRIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778979
发货至: 中国
  • 抗原 See all SYNCRIP 抗体
    SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 49
    • 39
    • 38
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 豚鼠, 马
    宿主
    • 61
    • 3
    克隆类型
    • 52
    • 12
    多克隆
    标记
    • 30
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYNCRIP antibody is un-conjugated
    应用范围
    • 30
    • 23
    • 14
    • 14
    • 13
    • 11
    • 11
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    IEIVFAKPPD QKRKERKAQR QAAKNQMYDD YYYYGPPHMP PPTRGRGRGG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against SYNCRIP. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SYNCRIP
    Top Product
    Discover our top product SYNCRIP Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 623 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ting, Wen, Liu, Hsieh-Li, Li, Lin-Chao: "The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).

    Groen, Fumoto, Blokhuis, Engelen-Lee, Zhou, van den Heuvel, Koppers, van Diggelen, van Heest, Demmers, Kirby, Shaw, Aronica, Spliet, Veldink, van den Berg, Pasterkamp: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).

  • 抗原
    SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))
    别名
    SYNCRIP (SYNCRIP 产品)
    别名
    GRY-RBP antibody, GRYRBP antibody, HNRNPQ antibody, HNRPQ1 antibody, NSAP1 antibody, PP68 antibody, hnRNP-Q antibody, 2610109K23Rik antibody, 4632417O19Rik antibody, Nsap1 antibody, Nsap1l antibody, pp68 antibody, nsap1 antibody, wu:fe02c03 antibody, wu:fe47h09 antibody, SYNCRIP antibody, hnrpq1 antibody, gry-rbp antibody, rp1-3j17.2 antibody, synaptotagmin binding cytoplasmic RNA interacting protein antibody, synaptotagmin binding, cytoplasmic RNA interacting protein antibody, synaptotagmin binding cytoplasmic RNA interacting protein S homeolog antibody, SYNCRIP antibody, Syncrip antibody, syncrip antibody, syncrip.S antibody
    背景
    Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly(A) and poly(U) RNA sequences.
    Alias Symbols: GRY-RBP, NSAP1, RP1-3J17.2, dJ3J17.2, pp68, PP68, GRYRBP, HNRPQ1, hnRNP-Q
    Protein Interaction Partner: FUS, PRMT8, UBC, SPRTN, SUMO2, SUMO3, STAU1, MDM2, RPA3, RPA2, RPA1, RNF2, EED, rev, GNB2L1, IQGAP1, RPS21, RPL24, RPL23A, PSMD7, RPSA, IARS, PRMT1, HNRNPU, FKBP3, MAP1S, C14orf166, RPS27L, NELFB, PARK2, FBXO6, TARDBP, CSF2, CD81, IGSF8, HMGA2, ICAM1, HMG
    Protein Size: 623
    分子量
    69 kDa
    基因ID
    10492
    NCBI登录号
    NM_006372, NP_006363
    UniProt
    O60506
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