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Interleukin enhancer-binding factor 3 (ILF3) (N-Term) 抗体

ILF3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN183971
发货至: 中国
  • 抗原 See all Interleukin enhancer-binding factor 3 (ILF3) 抗体
    Interleukin enhancer-binding factor 3 (ILF3)
    抗原表位
    • 4
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    • 2
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    • 2
    • 1
    • 1
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    N-Term
    适用
    • 57
    • 40
    • 37
    • 14
    • 11
    • 11
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    • 5
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    • 2
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    • 1
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    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马
    宿主
    • 53
    • 2
    • 1
    克隆类型
    • 46
    • 11
    多克隆
    标记
    • 43
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    非结合性
    应用范围
    • 37
    • 17
    • 11
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    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ALKAVSDWID EQEKGSSEQA ESDNMDVPPE DDSKEGAGEQ KTEHMTRTLR
    预测反应
    Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against ILF3. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ILF3
    Top Product
    Discover our top product ILF3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 702 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Interleukin enhancer-binding factor 3 (ILF3)
    别名
    ILF3 (ILF3 产品)
    别名
    CBTF antibody, DRBF antibody, DRBP76 antibody, MMP4 antibody, MPHOSPH4 antibody, MPP4 antibody, NF-AT-90 antibody, NF110 antibody, NF110b antibody, NF90 antibody, NF90a antibody, NF90b antibody, NFAR antibody, NFAR-1 antibody, NFAR2 antibody, TCP110 antibody, TCP80 antibody, MBII-26 antibody, ilf3 antibody, wu:fb37d07 antibody, wu:fb94b02 antibody, zgc:77030 antibody, 4F.1 antibody, cbtf122 antibody, ilf3-A antibody, ubp3 antibody, ubp4 antibody, xilf3 antibody, interleukin enhancer binding factor 3 antibody, interleukin enhancer binding factor 3b antibody, interleukin enhancer binding factor 3 S homeolog antibody, ILF3 antibody, Ilf3 antibody, ilf3b antibody, ilf3.S antibody
    背景
    ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: CBTF, DRBF, MMP4, MPP4, NF90, NFAR, NF110, NF90a, NF90b, NFAR2, TCP80, DRBP76, NF110b, NFAR-1, TCP110, MPHOSPH4, NF-AT-90
    Protein Interaction Partner: PLSCR1, UBC, FBXW11, RBPMS, HUWE1, MDM2, AURKA, SUMO2, SUMO3, STAU1, IVNS1ABP, LGR4, ERG, RPA3, RPA2, RPA1, EZH2, HNRNPL, SUZ12, RNF2, BMI1, EED, VHL, VEGFA, rev, FBXO6, TARDBP, CSF2, EIF2AK2, ICAM1, IGSF8, SNORD116-22, PABPC1, RNU2-4P, RNU5B-1, RNU5A-1,
    Protein Size: 702
    分子量
    76 kDa
    基因ID
    3609
    NCBI登录号
    NM_004516, NP_004507
    途径
    M Phase
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