XPO1 抗体 (Middle Region)
Quick Overview for XPO1 抗体 (Middle Region) (ABIN2778850)
抗原
See all XPO1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- IPAFKEHLRD FLVQIKEFAG EDTSDLFLEE REIALRQADE EKHKRQMSVP
-
预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Zebrafish: 79%
-
产品特性
- This is a rabbit polyclonal antibody against XPO1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human XPO1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 1071 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- XPO1 (Exportin 1 (XPO1))
-
别名
- XPO1
-
背景
-
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRM1, DKFZp686B1823, emb, exp1
Protein Interaction Partner: ABL1, UBC, HUWE1, ELAVL1, KEAP1, SUMO2, SUMO3, USP16, STAU1, CDC37L1, RNF2, rev, TUBB, SCPEP1, CAMK1D, DCPS, HSPA1L, HNRNPK, GNAI3, EEF2, CAPN2, TWF2, FERMT2, UBA3, NAE1, STK24, YWHAH, YWHAE, VCL, TUFM, PCYT2, PPP5C, PPP1CA, EGFR, LOC366310, CLN5, CLN3, S
Protein Size: 1071 -
分子量
- 123 kDa
-
基因ID
- 7514
-
NCBI登录号
- NM_003400, NP_003391
-
UniProt
- O14980
-
途径
- M Phase
抗原
-