Aconitase 1 抗体 (N-Term)
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- 抗原 See all Aconitase 1 (ACO1) 抗体
- Aconitase 1 (ACO1)
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aconitase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MSNPFAHLAE PLDPVQPGKK FFNLNKLEDS RYGRLPFSIR VLLEAAIRNC
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ACO1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACO1
- Top Product
- Discover our top product ACO1 Primary Antibody
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anti-Aconitase 1 (ACO1) (AA 251-443) antibody
ACO1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 329-443) antibodyACO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 26-243) antibodyACO1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 508-745) antibodyACO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 800-889) antibodyACO1 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 1-889) antibodyACO1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 780-889) antibodyACO1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2C1 unconjugated
anti-Aconitase 1 (ACO1) antibodyACO1 适用: 人, 小鼠, 大鼠, Hamster WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 527-719) antibodyACO1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) antibodyACO1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 889 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Aconitase 1 (ACO1)
- 别名
- ACO1 (ACO1 产品)
- 别名
- ACONS antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, IRP1 antibody, Acon1 antibody, Ratireb antibody, ratireb antibody, Aco1 antibody, AI256519 antibody, Aco-1 antibody, Irebp antibody, Irp1 antibody, aconitase 1 antibody, aconitase 1, soluble antibody, aconitase 1 L homeolog antibody, ACO1 antibody, Aco1 antibody, aco1.L antibody
- 背景
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ACO1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). It plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
Alias Symbols: IRP1, ACONS, IREB1, IREBP, IREBP1
Protein Interaction Partner: UBC, FBXL5, DCPS, STRAP, FUBP1, PSMG1, HIST1H2AB, LGALS1, CTPS1, C12orf57, APP, AKT1,
Protein Size: 889 - 分子量
- 98 kDa
- 基因ID
- 48
- NCBI登录号
- NM_002197, NP_002188
- UniProt
- P28271
- 途径
- Transition Metal Ion Homeostasis
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