UBTF 抗体 (Middle Region)
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- 抗原 See all UBTF 抗体
- UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 马, Cow, 兔, Pig, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBTF antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LESLPEEEQQ RVLGEEKMLN INKKQATSPA SKKPAQEGGK GGSEKPKRPV
- 预测反应
- Cow: 86%, Guinea Pig: 79%, Horse: 77%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against UBTF. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UBTF
- Top Product
- Discover our top product UBTF Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 764 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
- 别名
- UBTF (UBTF 产品)
- 别名
- NOR-90 antibody, UBF antibody, UBF-1 antibody, UBF1 antibody, A930005G04Rik antibody, Tcfubf antibody, wu:fj38c10 antibody, si:dz180g5.3 antibody, ubf antibody, Ubtf antibody, ubf1 antibody, xUBF antibody, xUBFbeta2 antibody, UBTF antibody, nor-90 antibody, ubf2 antibody, ubtf antibody, upstream binding transcription factor, RNA polymerase I antibody, upstream binding transcription factor, RNA polymerase I L homeolog antibody, upstream binding transcription factor, RNA polymerase I S homeolog antibody, UBTF antibody, Ubtf antibody, ubtf antibody, ubtf.L antibody, ubtf.S antibody
- 背景
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UBTF is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1. Two UBTF polypeptides, of 94 and 97 kD, exist in the human. UBTF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxesUpstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NOR-90, UBF, UBF1, UBF-1
Protein Interaction Partner: UBC, MDM2, RNF2, Dlg4, ESR1, CDK4, CDK2, CCNE1, CCND1, WDR70, YEATS4, RB1, GRK5, KAT5, SIRT7, POLR1A, MYBBP1A, HDAC1, RUNX2, SUMO2, SMARCA5, MAPK3, MAPK1, SUMO1, PIK3CA, IRS1, TAF1D, tat, MCRS1, TLE1, ACTN4, POLR1E, CHGB, SMURF1, TCOF1, MAD1L1, ZMYM2, SER
Protein Size: 764 - 分子量
- 89 kDa
- 基因ID
- 7343
- NCBI登录号
- NM_014233, NP_055048
- UniProt
- P17480
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