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PPFIBP1 抗体 (N-Term)

PPFIBP1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777159
发货至: 中国
  • 抗原 See all PPFIBP1 抗体
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    抗原表位
    • 10
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, Pig, 斑马鱼
    宿主
    • 31
    克隆类型
    • 31
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPFIBP1 antibody is un-conjugated
    应用范围
    • 24
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    PFMGSLRALH LVEDLRGLLE MMETDEKEGL RCQIPDSTAE TLVEWLQSQM
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against PPFIBP1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PPFIBP1
    Top Product
    Discover our top product PPFIBP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 170 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    别名
    PPFIBP1 (PPFIBP1 产品)
    别名
    liprin-beta-1 antibody, L2 antibody, SGT2 antibody, hSGT2 antibody, hSgt2p antibody, 4632409B19Rik antibody, AW214454 antibody, AW261454 antibody, PPFIA binding protein 1 antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antibody, Ppfibp1 antibody, ppfibp1 antibody, ppfibp1.S antibody, PPFIBP1 antibody
    背景
    PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: L2, hSGT2, hSgt2p, SGT2
    Protein Interaction Partner: VCP, TP53, CDKN1A, CEP76, CEP250, LATS2, YWHAQ, YWHAB, UBC, GRK5, SH3KBP1, ELAVL1, YWHAG, S100A4, PPFIA1, PPFIA3, PPFIA2, PPFIBP1, PTPRM, SFN,
    Protein Size: 170
    分子量
    19 kDa
    基因ID
    8496
    NCBI登录号
    NM_177444, NP_803193
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