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TNNT1 抗体 (Middle Region)

TNNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777153
发货至: 中国
  • 抗原 See all TNNT1 抗体
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    抗原表位
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 26
    • 13
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼
    宿主
    • 24
    • 6
    • 1
    克隆类型
    • 27
    • 4
    多克隆
    标记
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNT1 antibody is un-conjugated
    应用范围
    • 24
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    WIHQLESEKF DLMAKLKQQK YEINVLYNRI SHAQKFRKGA GKGRVGGRWK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against TNNT1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human TNNT1
    Top Product
    Discover our top product TNNT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 278 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    别名
    TNNT1 (TNNT1 产品)
    别名
    ANM antibody, NEM5 antibody, STNT antibody, TNT antibody, TNTS antibody, TNNI1 antibody, AW146156 antibody, Tnt antibody, sTnT antibody, ssTnT antibody, Fang2 antibody, tnTs antibody, Tnnt antibody, zgc:193831 antibody, zgc:193865 antibody, troponin T1, slow skeletal type antibody, troponin I1, slow skeletal type antibody, troponin T1, skeletal, slow antibody, troponin T1, slow skeletal type S homeolog antibody, troponin T type 1 (skeletal, slow) antibody, TNNT1 antibody, TNNI1 antibody, Tnnt1 antibody, tnnt1.S antibody, tnnt1 antibody
    背景
    TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: ANM, MGC104241, TNT, STNT, TNTS
    Protein Interaction Partner: CCDC136, TFIP11, LDOC1, MORF4L1, TBPL1, TPM3, TPM1, TNNT1, NFE2L2, KRT40, UBC, PI4KA, SERPINA4, OSM, MARS, HSP90AB1, FYN, EEF1G, DDX5, CHD3, BLOC1S2, C2orf44, ZNF768, ZNF250, ZC3H15, NAGK, HMP19, TRA2A, TMEM98, ARMC8, OSBP2, ZKSCAN5, LARP1, NACAD, SNW1, S
    Protein Size: 278
    分子量
    33 kDa
    基因ID
    7138
    NCBI登录号
    NM_003283, NP_003274
    UniProt
    P13805
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