MGMT 抗体 (Middle Region)
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Quick Overview for MGMT 抗体 (Middle Region) (ABIN2777118)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ISYQQLAALA GNPKAARAVG GAMRGNPVPI LIPCHRVVCS SGAVGNYSGG
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预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%
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产品特性
- This is a rabbit polyclonal antibody against MGMT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MGMT
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anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 32-210) antibody
MGMT 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1A11F8 unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 101-207) antibodyMGMT 适用: 大鼠 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (N-Term) antibodyMGMT 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182) antibodyMGMT 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibodyMGMT 适用: 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182), (C-Term) antibodyMGMT 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19082 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 207 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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别名
- MGMT
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背景
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MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Alias Symbols: -
Protein Interaction Partner: UBC, BRCA2, ANXA2, ANXA1, SLC25A6, SLC25A4, ACTB, CCNB1, FBL, EEF1B2, EEF1A2, EEF1A1, DDX5, CDKN1A, CDK2, CDK1, H2BFM, FBXO27, TUBA1C, ANP32E, IL25, DDX24, CDK12, FBXO2, USP19, TUBB4B, PRPF4, RNF8, EIF3H, CDK10, HIST1H4A, HIST1H2AM, HIST3H3, SMC1A, YWHAZ,
Protein Size: 207 -
分子量
- 22 kDa
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基因ID
- 4255
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NCBI登录号
- NM_002412, NP_002403
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UniProt
- P16455
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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