CYP2C9 抗体 (C-Term)
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- 抗原 See all CYP2C9 抗体
- CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 马, Pig, 兔, Cow, 犬, 绵羊, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP2C9 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AGMELFLFLT SILQNFNLKS LVDPKNLDTT PVVNGFASVP PFYQLCFIPV
- 预测反应
- Cow: 85%, Dog: 83%, Guinea Pig: 75%, Horse: 83%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 77%, Rat: 83%, Sheep: 83%
- 产品特性
- This is a rabbit polyclonal antibody against CYP2C9. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2C9
- Top Product
- Discover our top product CYP2C9 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 490 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
- 别名
- CYP2C9 (CYP2C9 产品)
- 别名
- CPC9 antibody, CYP2C antibody, CYP2C10 antibody, CYPIIC9 antibody, P450IIC9 antibody, cytochrome P450 family 2 subfamily C member 9 antibody, CYP2C9 antibody
- 背景
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CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that CYP2C9 gene is polymorphic.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPC9, CYP2C, CYP2C10, MGC149605, MGC88320, P450 MP-4, P450 PB-1, P450IIC9, CYPIIC9
Protein Interaction Partner: POR, CYP2D6, STAMBP, STAT5A, RNF32, ECSIT, MAST1, CDC37, RAB3D,
Protein Size: 490 - 分子量
- 55 kDa
- 基因ID
- 1559
- NCBI登录号
- NM_000771, NP_000762
- UniProt
- P11712
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