CYP2D6 抗体 (N-Term)
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- 抗原 See all CYP2D6 抗体
- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 绵羊, Pig, 兔, 犬, 豚鼠, 马, Cow, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP2D6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- RPPVPITQIL GFGPRSQGVF LARYGPAWRE QRRFSVSTLR NLGLGKKSLE
- 预测反应
- Cow: 91%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Sheep: 86%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against CYP2D6. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CYP2D6
- Top Product
- Discover our top product CYP2D6 Primary Antibody
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anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 236-472) antibody
CYP2D6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 315-347), (C-Term) antibodyCYP2D6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) antibodyCYP2D6 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 268-457) antibodyCYP2D6 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 315-347) antibodyCYP2D6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) antibodyCYP2D6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 91-190) antibodyCYP2D6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) antibodyCYP2D6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 101-150) antibodyCYP2D6 适用: 人, 猴, 绵羊, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 20-230) antibodyCYP2D6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 497 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
- 别名
- CYP2D6 (CYP2D6 产品)
- 别名
- CPD6 antibody, CYP2D antibody, CYP2D7AP antibody, CYP2D7BP antibody, CYP2D7P2 antibody, CYP2D8P2 antibody, CYP2DL1 antibody, CYPIID6 antibody, P450-DB1 antibody, P450C2D antibody, P450DB1 antibody, CYP2D42 antibody, MGC64445 antibody, cyp2d2 antibody, cyp2d6-a antibody, CYP2D6 antibody, cytochrome P450 family 2 subfamily D member 6 antibody, cytochrome P450, family 2, subfamily D, polypeptide 6 antibody, cytochrome 2D6 antibody, cytochrome P450 family 2 subfamily D member 6 S homeolog antibody, cytochrome P450 2D6 antibody, cytochrome P450 2D6-like antibody, CYP2D6 antibody, cyp2d6-b antibody, cyp2d6.S antibody, cyp2d6 antibody, LOC100988273 antibody
- 背景
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CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20 % of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug, sparteine and propafenone, both anti-arrythmic drugs, and amitryptiline, an anti-depressant.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20 % of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug, sparteine and propafenone, both anti-arrythmic drugs, and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population, certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RP4-669P10.2, CPD6, CYP2D, CYP2D@, CYP2DL1, MGC120389, MGC120390, P450-DB1, P450C2D, CYPIID6, P450DB1, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2
Protein Interaction Partner: CYP2D6, CYP2C9, POR, CYB5A,
Protein Size: 497 - 分子量
- 55 kDa
- 基因ID
- 1565
- NCBI登录号
- NM_000106, NP_000097
- UniProt
- P10635
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