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LBP 抗体 (C-Term)

This anti-LBP antibody is a 兔 多克隆 antibody detecting LBP in WB 和 IHC. Suitable for 人, Cow, Pig 和 马.
产品编号 ABIN2776869
发货至: 中国

Quick Overview for LBP 抗体 (C-Term) (ABIN2776869)

抗原

See all LBP 抗体
LBP (Lipopolysaccharide Binding Protein (LBP))

适用

  • 45
  • 21
  • 21
  • 11
  • 9
  • 9
  • 3
  • 3
  • 3
  • 2
  • 2
人, Cow, Pig, 马

宿主

  • 56
  • 24
  • 5
  • 4

克隆类型

  • 60
  • 29
多克隆

标记

  • 70
  • 9
  • 3
  • 3
  • 2
  • 2
This LBP antibody is un-conjugated

应用范围

  • 65
  • 43
  • 33
  • 28
  • 27
  • 10
  • 8
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    FLKPGKVKVE LKESKVGLFN AELLEALLNY YILNTFYPKF NDKLAEGFPL

    预测反应

    Cow: 86%, Horse: 85%, Human: 100%, Pig: 79%

    产品特性

    This is a rabbit polyclonal antibody against LBP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human LBP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 481 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    LBP (Lipopolysaccharide Binding Protein (LBP))

    别名

    LBP

    背景

    LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
    Alias Symbols: MGC22233, BPIFD2
    Protein Interaction Partner: TSC22D4, PYCRL, TRA2A, PRDX4, SETD1A, CBFA2T2, BAG6, PSMA3, SMAD3, HSPB1, FTH1, C4BPA, BST1, CAMP, APOA1, RPS21, CD14, CFHR1, IRF6,
    Protein Size: 481

    分子量

    53 kDa

    基因ID

    3929

    NCBI登录号

    NM_004139, NP_004130

    UniProt

    P18428

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
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